Gene: [00.0/SLC5A5] solute carrier family 5 (sodium iodide symporter), member 5; hypothyroidism, congenital (due to sodium iodide symporter defect); thyroid hormonogenesis, genetic defect in, I (MIM:274400); [NIS ]

FUN

The SLC5A5 gene product is a sodium-iodide symporter and actively transports iodide across the basolateral plasma membrane of the thyroid follicular cells."

REF

PAT,MUT,FOG "Fujiwara H &: Nature Genet, 16, N2, 124-125, 1997
COD,SEQ,EVO "Smanik PA &: BBRC, 226, N2, 339-345, 1996

KEY

horm, trp, ion, mem

CLA

coding, basic

LOC

RS

MIM

MIM: 601843

SYN

NIS