Gene: [05q11/LARS] leucyl-tRNA synthetase;

FUN

Systematic name: L-leucine:tRNA(Leu) ligase (AMP-forming). The catalyzed reaction: ATP + L-leucine + tRNA(Leu) = AMP + pyrophosphate + L-leucyl-tRNA(Leu)."

FAG

Several genes coding for various aminoacyl-tRNA synthetases are mapped to chr 5, see GEM:05p1/TARS."

REF

LOC,CYG "Dana S, Wasmuth JJ: Mol Cell Biol, 2, 1220-1228, 1982
LOC,CYG "Gerken SC &: Somat Cell Mol Genet, 12, 519-522, 1986
LOC,CYG "Giles RE &: Somat Cell Genet, 6, N5, 667-687, 1980
LOC,CYG "Lobaton CD &: Mol Cell Biol, 4, 475-483, 1984

KEY

aac, trl

CLA

coding, basic

LOC

05 q11

MIM

MIM: 151350

EZN

ENZYME: 6.1.1.4