Gene: [05q2/HSD17B4] hydroxysteroid (17-beta) dehydrogenase 4; estradiol 17 beta-dehydrogenase 4; D-bifunctional protein deficiency;

COM

Leenders-1997 assigned 17-beta hydroxysteroid dehydrogenase IV gene to Chr 5q2 by fluorescence in situ hybridization."

FUN

[1] Systematic name: 11-beta-hydroxysteroid:NADP+ 11-oxidoreductase.
[2] Catalysed reaction: 11-beta-hydroxysteroid + NADP(+) = 11-oxosteroid + NADPH."

REF

CLO,SEQ,EXP "Adamski J &: Biochem J, 311, 437-443, 1995
LOC "Leenders F &: Genomics, 37, N3, 403-404, 1996
MUT "van Grunsven EG &: PNAS, 95, N5, 2128-2133, 1998

SWI

SWISSPROT: P51659

KEY

horm, sex

CLA

coding, basic

LOC

05 q2

MIM

MIM: 601860

EZN

ENZYME: 1.1.1.62

Ссылки: