Gene: [07q31/SPAM1] sperm adhesion molecule 1; sperm surface protein PH-20 (zona pellucida binding); hyaluronidase (hyaluronoglucosaminidase);

FUN

The protein aids in penetrating the layer of cumulus cells (that surrounds the egg) by digesting hyaluronic acid before reaching the zona pellucida."

REF

CLO,SEQ "Gmachl M &: FEBS Lett, 336, 545-548, 1993
COD,SEQ,STR,LOC "Jones MH &: Genomics, 29, 796-800, 1995
FUN "Lin Y &: J Cell Biol, 125, 1157-1163, 1994
CLO,SEQ "Lin Y &: PNAS, 90, 10071-10075, 1993

SWI

SWISSPROT: P38567

KEY

mem, carb

CLA

coding, basic

LOC

07 q31

MIM

MIM: 600930

EZN

ENZYME: 3.2.1.35

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