Gene: [10q2/ACADSB] acyl-Coenzyme A dehydrogenase, short/branched chain;

COM

The ACADSB gene is mapped to chr 10 q25-26 using Southern blot analysis of DNA from a panel of human/rodent somatic hybrids and FISH (Arden, 1995)."

EVO

The ACADSB gene is a member of the acyl-Coenzyme A dehydrogenase gene family with the greatest homology (38%)to the short chain ACAD (GEM:12q2/ACADS)."

FUN

The ACADSB protein acts toward the various short/branched chain acyl-CoA derivatives with the greatest activity against 2-methyl short/branched chain acyl-CoAs (Rozen, 1994)."

REF

PRO,LOC "Arden KC &: Genomics, 25, 743-745, 1995
COD,SEQ,EXP "Rozen R &: Genomics, 24, 280-287, 1994

KEY

lip

CLA

coding, basic

LOC

10 q25-26

MIM

MIM: 600301

EZN

ENZYME: 1.3.99.3