Gene: [17p133/BCRR] active BCR-related gene; breakpoint cluster region-related gene (active); [ABR MDB ]

FUN

ABR encodes a GTPase activating protein for p21rac members of the ras superfamily (Heisterkamp-1993; Tan-1993)."

ASS

McDonald-1994 found that the ABR locus was deleted in 7 of 8 informative cases of medulloblastoma."

REF

POL "DiSilvestre D &: NAR, 18, 5924, 1990
LOC,SEQ,EXP,EVO "Heisterkamp N &: JBC, 268, 16903-16906, 1993
IDN,COD,POL,EXP,LOC "Heisterkamp N &: NAR, 17, 8821-8831, 1989
POL,ASS,PAT "McDonald JD &: Genomics, 23, 229-232, 1994
LOC,LIN,MAF "Morris C &: Oncogene, 10, 1009-1011, 1995
MOP,EXP "Tan EC &: JBC, 268, 27291-27298, 1993
LOC,REL "Truedsson L &: Scand J Rheumatol, 19, 326-332, 1990

KEY

onc, hem, chr

CLA

coding, basic

LOC

17 p13.3

MIM

MIM: 600365

SYN

ABR MDB