Gene: [19q131/UPK1A] uroplakin 1A;

SUM

The asymmetric unit membrane (AUM) of mammalian bladder epithelium is believed to be involved in strengthening and stabilizing the urothelial apical surface, thus preventing the cells from rupturing during bladder distention. The major protein components of AUM are uroplakin (UPK) 1A, UPK1B (GEM:03q/UPK1B), UPK2 (GEM:00.0/UPK2), and UPK3 (GEM:00.0/UPK3)."

REF

EVO,MAM "Yu J &: J Cell Biol, 125, N1, 171-182, 1994

KEY

mem

CLA

coding, basic

LOC

19 q13.1

MIM

?