Gene: [21q223/PKNOX1] PBX/knotted 1 homeobox 1;

COM

By PCR amplification, hybridization, and genetic linkage analysis PKNOX1 was mapped to Chr 21q22.3 between markers D21S212 and D21S25 on YAC350F7 (Chen-1997)."

MOP

PKNOX1 encodes a homeodomain-containing polypeptide of 436 amino acids. The homeodomain is closely related to those of the mammalian PBX family (such as mouse Meis1) and the plant knotted 1 family (involved in plant development)."

REF

CLO,COD,SEQ,EVO,DOM,LOC "Chen H &: Genomics, 41, 193-200, 1997

SWI

SWISSPROT: P55347

KEY

home

CLA

coding, basic

LOC

21 q22.3

MIM

MIM: 602100