Gene: [22q112/HIRA] HIR (histone cell cycle regulation defective, S. cerevisiae) homolog A; Tup-like enhancer of split 1; [TUPLE1 ]

FUN

A putative transcription regulator with a sequence similar to that of the yeast TUP1 gene (Halford-1993). The protein product of the TUPLE1 gene contains WD40 domains, motifs thought to be involved in protein-protein interactions."

GEN

The gene length: 60 kb (app.); exons: 24 (Llevadot-1996).

FAG

See GEM:22q112/DGCR[:FAG].

REF

PRO,LOC "Halford S &: Hum Mol Genet, 2, 2099-2107, 1993
COD,SEQ,MOP,EXP "Lamour V &: Hum Mol Genet, 4, 791-799, 1995
GEN,SEQ "Llevadot R &: Mammal Genome, 7, N12, 911-914, 1996

KEY

trc

CLA

coding, basic

LOC

22 q11.2

MIM

MIM: 600237

SYN

TUPLE1